By Lorenzo Tomatis (auth.), Lorenzo Tomatis (eds.)
Air pollutants and Human Cancer analyzes the proof for the prospective contribution of pollution to the starting place of human melanoma. distinct specialists in numerous components of melanoma examine record on: - pollution and melanoma: an previous and a brand new challenge; - assets, nature and degrees of air pollution; - size and tracking of person exposures; - experimental facts for the carcinogenicity of air pollution; - epidemiological proof on pollution and melanoma; - melanoma probability estimation and prevention.
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Additional resources for Air Pollution and Human Cancer
International Agency for Research on Cancer, Lyon 1983 Ahland E et al: Air Pollution and Cancer. Investigation of hazardous constituents from various emission sources for their carcinogenic impact. MOnchener Med Wochenschr 1985 (127):218-221 Pott F: Pyrolytic profiles of polycyclic aromatic hydrocarbons and lung cancer risk - data evaluation. Staubreinhalt Luft 1985 (45):369-379 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 Pitts IN Jr: Nitration of gaseous polyaromatic hydrocarbons in simulated and ambient urban atmospheres: a source of mutagenic nitroarenes.
The adduct patterns resembled those obtained from Silesian coke workers, suggesting that derivates of coal burning and extraction may contribute to the finding. Some evidence of pollution-related cancer risk has been obtained in the Cracow area of Poland (see Chapter 5). Cytogenetic studies where chromosomal aberrations, sister chromatid exchanges and micronuclei are measured, have been used 40 K. Hemminki Table 3. 5(15)1 29 Smoking. aromatic postlabelling (Lung) 1-30 5-10 30 Smoking, aromatic PAH postlabelling and immunoassay (WBC) 1-30 10 31-33 Foundries, cokeries postlabelling and immunoassay (WBC) 1-1000 100 34-40 Background, aromatic (WBC) 1-10 2-20 28 one individual; WBC = white blood cells to monitor the effects of exposure to chemicals.
00003 6 27 cadmium, which are mainly obtained by ingestion of polluted food. Their origin is, therefore, air pollution (see Chapter 2). An international comparison was made between teachers who were not subject to occupational exposure to these compounds (Figs. 4 and 5) [18). lg/l (nonsmokers), respectively, in non-exposed individuals. The teachers in Mexico exceed these values for lead; non-smoking teachers in Belgium and Japan are just at that level for cadmium. The marked effect of smoking on the cadmium levels is clearly seen in Figure 5.
Air Pollution and Human Cancer by Lorenzo Tomatis (auth.), Lorenzo Tomatis (eds.)