Read e-book online Acute Exposure Guideline Levels for Selected Airborne PDF

By National Research Council, Board on Environmental Studies and Toxicology, Committee on Toxicology, Committee on Acute Exposure Guideline Levels

This booklet is the 6th quantity within the sequence Acute publicity instruction degrees for Selected Airborne Chemicals, and comprises AEGLs for chemical compounds resembling ammonia, nickel carbonyl and phosphine, between others.

At the request of the dept of safeguard, the nationwide examine Council has reviewed the proper clinical literature compiled via knowledgeable panel and tested Acute publicity instruction degrees (AEGLs) for 12 new chemical compounds. AEGLs symbolize publicity degrees lower than which adversarial future health results are usually not more likely to take place and are worthwhile in responding to emergencies corresponding to unintentional or intentional chemical releases locally, the place of work, transportation, the army, and for the remediation of infected sites.

Three AEGLs are authorized for every chemical, representing publicity degrees that bring about: 1) awesome yet reversible pain; 2) long-lasting health and wellbeing results; and three) life-threatening well-being impacts.

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Extra resources for Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 6

Example text

This study is summarized with all other multiple-exposure inhalation animal studies (described in the following sections) in Table 1-6. In an experiment to evaluate the effect of inhaled allylamine on EKGs, young adult Fischer 344 rats (5/sex) were exposed to 100 or 150 ppm for 6 h/day for 10 days over a 3-week-period (Lynch et al. 1983). Allylamine vapor was generated by metering liquid allylamine into the tangential air-feed manifold air stream at the top of the inhalation chamber; the concentration was monitored with an infrared analyzer.

No other details of the allylamine concentration analysis were given. 2. Nonlethal Toxicity Inhalation studies in which no lethality occurred were conducted using rats, mice, rabbits, and monkeys. The results are summarized in Table 1-7. 1. 7 kg) were administered 73 exposures of 40 ppm allylamine for 4 h/day, 5 days/week, and were subsequently examined for cardiac effects (Guzman et al. 1961). Exposure was in a 200-L steel chamber into which allylamine was delivered by a constantdrive syringe and vaporized; the air allylamine concentrations were measured periodically.

No other details of the allylamine concentration analysis were given. 2. Nonlethal Toxicity Inhalation studies in which no lethality occurred were conducted using rats, mice, rabbits, and monkeys. The results are summarized in Table 1-7. 1. 7 kg) were administered 73 exposures of 40 ppm allylamine for 4 h/day, 5 days/week, and were subsequently examined for cardiac effects (Guzman et al. 1961). Exposure was in a 200-L steel chamber into which allylamine was delivered by a constantdrive syringe and vaporized; the air allylamine concentrations were measured periodically.

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Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 6 by National Research Council, Board on Environmental Studies and Toxicology, Committee on Toxicology, Committee on Acute Exposure Guideline Levels


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